Treatment implications of posterior fossa ependymoma subgroups
نویسندگان
چکیده
منابع مشابه
Treatment implications of posterior fossa ependymoma subgroups
Posterior fossa ependymoma comprises two distinct molecular entities, ependymoma_posterior fossa A (EPN_PFA) and ependymoma_posterior fossa B (EPN_PFB), with differentiable gene expression profiles. As yet, the response of the two entities to treatment is unclear. To determine the relationship between the two molecular subgroups of posterior fossa ependymoma and treatment, we studied a cohort o...
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Despite the histological similarity of ependymomas from throughout the neuroaxis, the disease likely comprises multiple independent entities, each with a distinct molecular pathogenesis. Transcriptional profiling of two large independent cohorts of ependymoma reveals the existence of two demographically, transcriptionally, genetically, and clinically distinct groups of posterior fossa (PF) epen...
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ژورنال
عنوان ژورنال: Chinese Journal of Cancer
سال: 2016
ISSN: 1944-446X
DOI: 10.1186/s40880-016-0155-6